If administered intravenously, treatment with medications that can dissolve a clot must be started within 4.5 hours of the onset of symptoms. The sooner these medications are administered, the better. Your chances of survival increase with prompt treatment, which may help lessen problems. The most effective treatment for ischemic stroke is an intravenous injection of recombinant tissue plasminogen activator, commonly known as alteplase (Activase) or tenecteplase. Within the first three hours, TPA is often injected into a vein in the arm. TPA can occasionally be administered up to 4.5 hours after the onset of stroke symptoms. This medication dissolves the blood clot that caused the stroke, restoring blood flow.
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